What is the deficiency associated with Kwashiorkor?

Kwashiorkor is a form of malnutrition that primarily arises from a deficiency of protein in the diet, despite the possible adequate intake of calories and other nutrients. This condition often occurs in regions where food availability is interrupted, particularly in developing countries, and is common in children who are weaned from breast milk and who do not receive sufficient protein in their diets.

The hallmark symptoms of Kwashiorkor include edema, an enlarged liver, fatty liver, skin lesions, and growth failure. The lack of protein affects the body's ability to produce vital proteins, including albumin, which helps maintain oncotic pressure and fluid balance in blood vessels. As a result, fluid leaks into the surrounding tissues, leading to swelling, or edema, particularly in the abdomen.

While other deficiencies, such as those of energy or fat, can lead to different types of malnutrition, they do not result in the unique physiological changes and symptoms observed in Kwashiorkor. Thus, protein deficiency is the defining characteristic of this condition.